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BLS wage data · May 2025

Medical Assistant Salary in South Carolina

Medical Assistants in South Carolina earn a median of $41,160 a year, or $19.79 an hour. That ranks South Carolina #37 of 51 states and is $4,530 less than the national median.

Median / year
$41,160
Median / hour
$19.79
Employed
12,110
National rank
#37of 51

Pay range in South Carolina

10th percentile$34,730
25th percentile$37,290
Median percentile$41,160
75th percentile$46,950
90th percentile$49,110

Medical Assistant pay by South Carolina metro area

Metro areaMedianJobs
Charlotte-Concord-Gastonia, NC-SC$46,5206,060
Charleston-North Charleston, SC$45,6002,320
Greenville-Anderson-Greer, SC$44,8602,550
Hilton Head Island-Bluffton-Port Royal, SC$43,610560
Spartanburg, SC$40,930620
Sumter, SC$40,780170
Columbia, SC$40,6802,190
Myrtle Beach-Conway-North Myrtle Beach, SC$38,950910
Florence, SC$38,790420
Augusta-Richmond County, GA-SC$38,4701,620

FAQ

How much does a medical assistant make in South Carolina?

The median annual wage is $41,160 ($19.79 per hour), according to the BLS for May 2025. That is $4,530 below the U.S. median of $45,690.

What do entry-level medical assistants make in South Carolina?

The lowest-paid 10% of South Carolina medical assistants earned $34,730 or less ($16.70/hour), a reasonable estimate for new graduates.

Where do medical assistants earn the most in South Carolina?

Charlotte-Concord-Gastonia, NC-SC has the highest metro median at $46,520.

How many medical assistants work in South Carolina?

About 12,110 medical assistants were employed in South Carolina in May 2025.